Growth Hormone 1 Antikörper (AA 58-187) (CF®647)

Produktnummer ABIN6163607

Dieses Anti-Growth Hormone 1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Growth Hormone 1 in IHC, IF und FACS. Geeignet für Human.

Kurzübersicht für Growth Hormone 1 Antikörper (AA 58-187) (CF®647) (ABIN6163607)

Target: Growth Hormone 1 (GH1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Growth Hormone 1 Antikörper ist konjugiert mit CF®647

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: GH-1371

Produktdetails anti-Growth Hormone 1 Antikörper (CF®647)

Bindungsspezifität: AA 58-187

Verwendungszweck: Mouse Monoclonal anti-Growth Hormone (GH/1371), CF647 Conjugate

Produktmerkmale: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A recombinant human Growth Hormone (GH) fragment (aa58-187) (exact sequence is proprietary)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Immunohistology (formalin) 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

Pituitary cells or Pituitary

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Andere Bezeichnung: Growth Hormone

Hintergrund: GH, GH-N, GH1, GHN, Growth hormone 1, Growth hormone, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin

Molekulargewicht: 20 kDa

Gen-ID: 2688, 655229

UniProt: P01241

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process