Der Kaninchen Polyklonal Anti-TET2-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, TET2 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Yu, Liu, Liu, Wang, Liu, Miao, Du, Yang: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).
Target
TET2
(Tet Methylcytosine Dioxygenase 2 (TET2))
Andere Bezeichnung
TET2
Hintergrund
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.,MDS,KIAA1546,TET2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,DNA Demethylation,TET2