Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TET2 Antikörper (AA 1833-2002)

TET2 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7159637
  • Target Alle TET2 Antikörper anzeigen
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    Bindungsspezifität
    • 17
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1833-2002
    Reaktivität
    • 47
    • 15
    • 6
    Human
    Wirt
    • 41
    • 8
    • 2
    Kaninchen
    Klonalität
    • 43
    • 8
    Polyklonal
    Konjugat
    • 33
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TET2 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 22
    • 11
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Methylcytosine dioxygenase TET2 protein (1833-2002AA)
    Isotyp
    IgG
    Top Product
    Discover our top product TET2 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    Andere Bezeichnung
    TET2 (TET2 Produkte)
    Synonyme
    KIAA1546 antikoerper, MDS antikoerper, Ayu17-449 antikoerper, E130014J05Rik antikoerper, mKIAA1546 antikoerper, RGD1311625 antikoerper, tet methylcytosine dioxygenase 2 antikoerper, TET2 antikoerper, Tet2 antikoerper
    Hintergrund

    Background: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.

    Aliases: FLJ20032 antibody, KIAA1546 antibody, MDS antibody, Methylcytosine dioxygenase TET2 antibody, Nbla00191 antibody, Probable methylcytosine dioxygenase TET2 antibody, Protein Ayu17 449 antibody, Tet 2 antibody, Tet methylcytosine dioxygenase 2 antibody, Tet oncogene 2 antibody, Tet oncogene family member 2 antibody, TET2 antibody, TET2_HUMAN antibody

    UniProt
    Q6N021
    Pathways
    Warburg Effekt
Sie sind hier: