ERCC3 Antikörper (AA 242-261)

Produktnummer ABIN614756

Produktdetails anti-ERCC3 Antikörper

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Bindungsspezifität: AA 242-261

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ERCC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: Recognizes an epitope located between aa242-261 of ERCC-3 (largest subunit of TFIIH).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography

Immunogen: Synthetic peptide corresponding to aa242-261 of Human ERCC-3.

Klon: 3G4

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.1 M Tris-HCl, pH 7.5.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (Add 40-50% Glycerol) at -20 °C for longer.

Details zu ERCC3

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Andere Bezeichnung: ERCC3 (ERCC3 Produkte)

Synonyme: BTF2 antikoerper, GTF2H antikoerper, RAD25 antikoerper, TFIIH antikoerper, XPB antikoerper, BTF2 p89 antikoerper, Ercc-3 antikoerper, wu:fc25f08 antikoerper, ERCC excision repair 3, TFIIH core complex helicase subunit antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 3 antikoerper, excision repair cross-complementation group 3 antikoerper, ERCC3 antikoerper, Ercc3 antikoerper, ercc3 antikoerper

Hintergrund: ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kD subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.Synonyms: BTF2-p89, Basic transcription factor 2 89 kDa subunit, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, ERCC-3, TFIIH 89 kDa subunit, TFIIH basal transcription factor complex helicase XPB subunit, XPB, XPBC, Xeroderma pigmentosum group B-complementing protein

Gen-ID: 2071

NCBI Accession: NP_000113

UniProt: P19447

Pathways: DNA Reparatur