Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ROCK1 Antikörper (AA 400-660)

Der Kaninchen Polyklonal Anti-ROCK1-Antikörper wurde für WB, IHC und IP validiert. Er ist geeignet, ROCK1 in Proben von Human zu detektieren.
Produktnummer ABIN6147066

Kurzübersicht für ROCK1 Antikörper (AA 400-660) (ABIN6147066)

Target

Alle ROCK1 Antikörper anzeigen
ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Reaktivität

  • 87
  • 63
  • 59
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Human

Wirt

  • 82
  • 9
Kaninchen

Klonalität

  • 68
  • 23
Polyklonal

Konjugat

  • 44
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser ROCK1 Antikörper ist unkonjugiert

Applikation

  • 73
  • 26
  • 26
  • 25
  • 21
  • 19
  • 17
  • 15
  • 11
  • 11
  • 6
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • Bindungsspezifität

    • 16
    • 16
    • 15
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-660

    Sequenz

    YSNRRYLSSA NPNDNRTSSN ADKSLQESLQ KTIYKLEEQL HNEMQLKDEM EQKCRTSNIK LDKIMKELDE EGNQRRNLES TVSQIEKEKM LLQHRINEYQ RKAEQENEKR RNVENEVSTL KDQLEDLKKV SQNSQLANEK LSQLQKQLEE ANDLLRTESD TAVRLRKSHT EMSKSISQLE SLNRELQERN RILENSKSQT DKDYYQLQAI LEAERRDRGH DSEMIGDLQA RITSLQEEVK HLKHNLEKVE GERKEAQDML N

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human ROCK1 (NP_005397.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:100

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

    Andere Bezeichnung

    ROCK1

    Hintergrund

    This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.,ROCK1,P160ROCK,ROCK-I,Cancer,Signal Transduction,G protein signaling,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,Death Receptor Signaling Pathway,TGF-b-Smad Signaling Pathway,ROCK1

    Molekulargewicht

    158 kDa

    Gen-ID

    6093

    UniProt

    Q13464

    Pathways

    Microtubule Dynamics, WNT Signalweg, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
Sie sind hier:
Chat with us!