RNF7 Antikörper (AA 1-113)

Produktnummer ABIN6147047

Dieses Anti-RNF7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RNF7 in WB und IF. Geeignet für Human.

Kurzübersicht für RNF7 Antikörper (AA 1-113) (ABIN6147047)

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RNF7 Antikörper

Bindungsspezifität: AA 1-113

Sequenz: MADVEDGEET CALASHSGSS GSKSGGDKMF SLKKWNAVAM WSWDVECDTC AICRVQVMDA CLRCQAENKQ EDCVVVWGEC NHSFHNCCMS LWVKQNNRCP LCQQDWVVQR IGK

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Andere Bezeichnung: RNF7

Hintergrund: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.,RNF7,CKBBP1,ROC2,SAG,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Endocrine & Metabolism,RNF7

Molekulargewicht: 9 kDa/10 kDa/11 kDa/12 kDa

Gen-ID: 9616

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity