Integrin beta 2 Antikörper
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- Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen
- Integrin beta 2 (ITGB2)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 2 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit, beta2 integrin). CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human. Negative with Canine (Dog).
- Aufreinigung
- Protein A Chromatography
- Klon
- MEM-48
- Isotyp
- IgG1
- Top Product
- Discover our top product ITGB2 Primärantikörper
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anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reaktivität: Human FACS, WB, IP, IHC (fro), IHC (p) Wirt: Maus Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 Reaktivität: Human FACS, WB, IP, IHC (fro), Func, IHC (p) Wirt: Maus Monoclonal MEM-48 unconjugated
anti-Integrin beta 2 (ITGB2) antibody (Biotin)ITGB2 Reaktivität: Human FACS, WB, IP, IHC (fro), IHC (p) Wirt: Maus Monoclonal MEM-48 Biotin
anti-Integrin beta 2 (ITGB2) antibody (FITC)ITGB2 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-48 FITC
anti-Integrin beta 2 (ITGB2) antibody (PE)ITGB2 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-48 PE
anti-Integrin beta 2 (ITGB2) (AA 70-170) antibodyITGB2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 Reaktivität: Maus FACS, WB, IP, IHC (fro), Func, IHC (p) Wirt: Ratte Monoclonal M18-2 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 559-700) antibodyITGB2 Reaktivität: Human FACS, WB, ELISA Wirt: Maus Monoclonal 3C11G5 unconjugated
anti-Integrin beta 2 (ITGB2) (AA 17-382) antibodyITGB2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 2 (ITGB2) antibodyITGB2 Reaktivität: Maus FACS, WB, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal M18-2 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, pH ~7.4 without preservatives
- Konservierungsmittel
- Without preservative
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- Target
- Integrin beta 2 (ITGB2)
- Andere Bezeichnung
- CD18 / ITGB2 (ITGB2 Produkte)
- Hintergrund
- CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. IIntegrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
- Gen-ID
- 3689
- Pathways
- NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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