IL1A Antikörper (AA 112-271)
Kurzübersicht für IL1A Antikörper (AA 112-271) (ABIN6142331)
Target
Alle IL1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 112-271
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Sequenz
- RSAPFSFLSN VKYNFMRIIK YEFILNDALN QSIIRANDQY LTAAALHNLD EAVKFDMGAY KSSKDDAKIT VILRISKTQL YVTAQDEDQP VLLKEMPEIP KTITGSETNL LFFWETHGTK NYFTSVAHPN LFIATKQDYW VCLAGGPPSI TDFQILENQA
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 112-271 of human IL1A (NP_000566.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IL1A (Interleukin 1 alpha (IL1A))
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Andere Bezeichnung
- IL1A
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Hintergrund
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.,IL1A,IL-1A,IL1,IL1-ALPHA,IL1F1,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,Cytokines,Interleukins,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,IL1A
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Molekulargewicht
- 30 kDa
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Gen-ID
- 3552
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UniProt
- P01583
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Pathways
- NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints
Target
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