Indian Hedgehog Antikörper (AA 202-411)
Kurzübersicht für Indian Hedgehog Antikörper (AA 202-411) (ABIN6142275)
Target
Alle Indian Hedgehog (IHH) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 202-411
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Sequenz
- GCFPAGAQVR LESGARVALS AVRPGDRVLA MGEDGSPTFS DVLIFLDREP HRLRAFQVIE TQDPPRRLAL TPAHLLFTAD NHTEPAARFR ATFASHVQPG QYVLVAGVPG LQPARVAAVS THVALGAYAP LTKHGTLVVE DVVASCFAAV ADHHLAQLAF WPLRLFHSLA WGSWTPGEGV HWYPQLLYRL GRLLLEEGSF HPLGMSGAGS
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 202-411 of human IHH (NP_002172.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Indian Hedgehog (IHH)
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Andere Bezeichnung
- IHH
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Hintergrund
- This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.,IHH,BDA1,HHG2,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Stem Cells,IHH
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Molekulargewicht
- 45 kDa
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Gen-ID
- 3549
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UniProt
- Q14623
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Pathways
- Hedgehog Signalweg
Target
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