PCNA Antikörper
Kurzübersicht für PCNA Antikörper (ABIN6139020)
Target
Alle PCNA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Green Monkey, Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human PCNA
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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Andere Bezeichnung
- PCNA
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Hintergrund
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],ATLD2,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,Signal Transduction,Stem Cells,Tumor biomarkers,PCNA
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Molekulargewicht
- 29 kDa
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Gen-ID
- 5111
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UniProt
- P12004
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie
Target
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