Complement Factor H Antikörper (AA 270-445)

Produktnummer ABIN6138452

Der Kaninchen Polyklonal Anti-Complement Factor H-Antikörper wurde für WB validiert. Er ist geeignet, Complement Factor H in Proben von Human zu detektieren.

Kurzübersicht für Complement Factor H Antikörper (AA 270-445) (ABIN6138452)

Target: Complement Factor H (CFH)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement Factor H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Complement Factor H Antikörper

Bindungsspezifität: AA 270-445

Sequenz: PYIPNGDYSP LRIKHRTGDE ITYQCRNGFY PATRGNTAKC TSTGWIPAPR CTLKPCDYPD IKHGGLYHEN MRRPYFPVAV GKYYSYYCDE HFETPSGSYW DHIHCTQDGW SPAVPCLRKC YFPYLENGYN QNHGRKFVQG KSIDVACHPG YALPKAQTTV TCMENGWSPT PRCIRV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-445 of human Complement factor H (NP_001014975.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Complement Factor H

Target: Complement Factor H (CFH)

Andere Bezeichnung: CFH

Hintergrund: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,CFH,AHUS1,AMBP1,ARMD4,ARMS1,CFHL3,FH,FHL1,HF,HF1,HF2,HUS,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFH

Molekulargewicht: 51 kDa/139 kDa

Gen-ID: 3075

UniProt: P08603

Pathways: Komplementsystem, Cellular Response to Molecule of Bacterial Origin