AGR2 Antikörper (AA 21-175)
Kurzübersicht für AGR2 Antikörper (AA 21-175) (ABIN6136646)
Target
Alle AGR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 21-175
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                                            Sequenz
- RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTEL
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                                            Kreuzreaktivität
- Human, Maus, Ratte
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                                            Produktmerkmale
- Polyclonal Antibodies
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                                            Aufreinigung
- Affinity purification
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                                            Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-175 of human AGR2 (NP_006399.1).
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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                                            Kommentare
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                        HIGH QUALITY 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))
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                                            Andere Bezeichnung
- AGR2
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                                            Hintergrund
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.,AGR2,AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8,PDIA17,XAG-2,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Stem Cells,AGR2
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                                            Molekulargewicht
- 19 kDa
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                                            Gen-ID
- 10551
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                                            UniProt
- O95994
 Target
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