Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
Zf, M
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This AGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the Central region of human AGR2.
AG2 antikoerper, GOB-4 antikoerper, HAG-2 antikoerper, PDIA17 antikoerper, XAG-2 antikoerper, Agr2h antikoerper, Gob-4 antikoerper, mAG-2 antikoerper, wu:fj29g05 antikoerper, zgc:112187 antikoerper, agr2 antikoerper, hag3 antikoerper, hag-3 antikoerper, bcmp11 antikoerper, MGC89004 antikoerper, XAgr2 antikoerper, agr2-A antikoerper, anterior gradient 2, protein disulphide isomerase family member antikoerper, anterior gradient 2 antikoerper, anterior gradient 3, protein disulphide isomerase family member antikoerper, anterior gradient 2, protein disulphide isomerase family member S homeolog antikoerper, AGR2 antikoerper, Agr2 antikoerper, agr2 antikoerper, agr3 antikoerper, agr2.S antikoerper
Hintergrund
Anterior gradient 2 (AGR2) is known as a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. AGR2 has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells (CTCs). Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells, but conditions leading to increased expression of AGR2 are not well understood.