Phospholipase C gamma 1 Antikörper (Tyr783)

Produktnummer ABIN5962019

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Phospholipase C gamma 1 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Phospholipase C gamma 1 Antikörper (Tyr783) (ABIN5962019)

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C gamma 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Phospholipase C gamma 1 Antikörper

Bindungsspezifität: Tyr783

Spezifität: 1 phosphatidyl D myo inositol 4 5 bisphosphate,1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1,Inositoltrisphosphohydrolase,Monophosphatidylinositol phosphodiesterase,NCKAP3,Phosphatidylinositol phospholipase C,Phosphoinositidase C,Phosphoinositide phospholipase C,Phosphoinositide phospholipase C-gamma-1,Phospholipase C 148,Phospholipase C gamma 1,Phospholipase C-gamma-1,Phospholipase C-II,PLC gamma 1,PLC II,PLC-148,PLC-gamma-1,PLC-II,PLC1,PLC148,Plcg1,PLCG1,PLCgamma1

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human PLC gamma1 around the non-phosphorylation site of Tyr783.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Phospholipase C gamma 1

Target: Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Andere Bezeichnung: PLC gamma1

Hintergrund: Plays a role in actin reorganization and cell migration. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Molekulargewicht: 149kDa

Gen-ID: 5335

UniProt: P19174

Pathways: RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling