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CHEK1 Antikörper (Ser317)

Name: CHEK1 Antikörper (Ser317)
SKU: ABIN5961570
Price: 449 EUR
Availability: InStock

CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Western Blotting (WB) image for anti-Checkpoint Kinase 1 (CHEK1) (Ser317) antibody (ABIN5961570) (CHEK1 Antikörper (Ser317))

1 image

Produktnummer ABIN5961570

Datenblatt (PDF)

Target Alle CHEK1 Antikörper anzeigen

CHEK1 (Checkpoint Kinase 1 (CHEK1))
Bindungsspezifität
36

29

26

19

13

8

7

6

5

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Ser317
Reaktivität
195

117

67

16

9

9

6

5

5

3

2

2

2

1

1
Human, Maus, Ratte
Wirt
204

14

6

5
Kaninchen
Passende Sekundärantikörper
Klonalität
205

25
Polyklonal
Konjugat
122

13

9

8

5

5

5

5

5

5

4

4

4

4

4

4

4

4

4

3

3

3

3
Dieser CHEK1 Antikörper ist unkonjugiert
Applikation
164

84

53

41

40

35

33

16

11

10

7

6

3

3

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität

C85740,Cell cycle checkpoint kinase,Checkpoint,S. pombe,homolog of,1,Checkpoint kinase 1,Checkpoint kinase 1 homolog (S. pombe),CHEK 1,Chek1,Chk 1,Chk1,CHK1 checkpoint homolog (S. pombe),CHK1,EC 2.7.11.1,rad27,Serine/threonine protein kinase Chk1,Serine/threonine-protein kinase CHK1,STT3,subunit of the oligosaccharyltransferase complex,homolog A (S. cerevisiae)

Aufreinigung

Affinity purification

Immunogen

Synthesized peptide derived from human Chk1 around the non-phosphorylation site of Ser317.

Isotyp

IgG

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CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer286) antibody
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anti-Checkpoint Kinase 1 (CHEK1) (pSer301) antibody
CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer296) antibody
CHEK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) antibody
CHEK1 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer345) antibody
CHEK1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibody
CHEK1 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB7845-RB18425 unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibody
CHEK1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

CHEK1 (Checkpoint Kinase 1 (CHEK1))

Andere Bezeichnung

Chk1 (CHEK1 Produkte)

Synonyme

An08g10320 antikoerper, AO090003000441 antikoerper, CHK1 antikoerper, chk1 antikoerper, C85740 antikoerper, Chk1 antikoerper, rad27 antikoerper, id:ibd2720 antikoerper, zgc:56093 antikoerper, CHEK1 antikoerper, checkpoint kinase 1 antikoerper, serine/threonine-protein kinase chk1 antikoerper, serine/threonine-protein kinase Chk1 antikoerper, CAMK/CAMKL/CHK1 protein kinase Chk1 antikoerper, checkpoint kinase 1 S homeolog antikoerper, CHEK1 antikoerper, ANI_1_2436074 antikoerper, AOR_1_768154 antikoerper, PTRG_04183 antikoerper, SJAG_01680 antikoerper, PAAG_04978 antikoerper, MCYG_03290 antikoerper, VDBG_03742 antikoerper, chek1.S antikoerper, Chek1 antikoerper, chek1 antikoerper

Hintergrund

Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by proteolysis of cyclins. Chk1 and Chk2 are involved in these processes as regulators of Cdks. Chk1 and Chk2 both function as essential components in the G2 DNA damage checkpoint by phosphorylating Cdc25C in response to DNA damage. Phosphorylation inhibits Cdc25C activity, thereby blocking mitosis. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. It has also been shown that Chk1 can phosphorylate Wee 1 in vitro, providing evidence that the hyperphosphorylated form of Wee 1, seen in cells delayed by Chk1 overexpression, is due to phosphorylation by Chk1.

Molekulargewicht

54kDa

Gen-ID

1111

UniProt

O14757

Pathways

p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur