JAK3 Antikörper (Tyr785)

Produktnummer ABIN5959635

Der Kaninchen Polyklonal Anti-JAK3-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, JAK3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für JAK3 Antikörper (Tyr785) (ABIN5959635)

Target: JAK3 (Janus Kinase 3 (JAK3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-JAK3 Antikörper

Bindungsspezifität: Tyr785

Spezifität: EC 2.7.10.2,JAK 3,JAK L,JAK-3,Jak3,JAK3 HUMAN,JAK3,JAKL,Janus kinase 3 (a protein tyrosine kinase,leukocyte),Janus kinase 3,Janus Kinase3,L JAK,L-JAK,Leukocyte janus kinase,LJAK,Protein tyrosine kinase leukocyte,Tyrosine protein kinase JAK3,Tyrosine-protein kinase JAK3

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Tyr785.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu JAK3

Target: JAK3 (Janus Kinase 3 (JAK3))

Andere Bezeichnung: JAK3

Hintergrund: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Molekulargewicht: 125kDa

Gen-ID: 3718

UniProt: P52333

Pathways: JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response