E2F1 Antikörper (Internal Region, Lys120)
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- Target Alle E2F1 Antikörper anzeigen
- E2F1 (E2F Transcription Factor 1 (E2F1))
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Bindungsspezifität
- Internal Region, Lys120
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser E2F1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- Reacts with human E2F-1 acK120 and acK125
- Kreuzreaktivität
- Maus
- Kreuzreaktivität (Details)
- May cross-react with E2F-1 from mouse and other species due to sequence homology
- Aufreinigung
- Antiserum
- Immunogen
- Synthetic peptide derived from internal domain of human E2F-1 protein containing acetyl lysine 120 and 125
- Isotyp
- IgG
- Top Product
- Discover our top product E2F1 Primärantikörper
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- Applikationshinweise
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Working dilution: Optimal dilutions should be determined by the end user.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Must be reconstituted in distilled water.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Haltbarkeit
- 24 months
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- Target
- E2F1 (E2F Transcription Factor 1 (E2F1))
- Andere Bezeichnung
- Transcription Factor E2F1 (E2F-1) (E2F1 Produkte)
- Synonyme
- CG6376 antikoerper, DRTF1/E2F antikoerper, DmE2F-1 antikoerper, Dmel\\CG6376 antikoerper, Dp antikoerper, E(Sev-CycE)3A antikoerper, E(var)3-93E antikoerper, E(var)3-95E antikoerper, E(var)93E antikoerper, E2F antikoerper, E2F-1 antikoerper, E2F1 antikoerper, E2f1 antikoerper, Evar(3)164 antikoerper, dE2F antikoerper, dE2F1 antikoerper, dE2f antikoerper, dE2f1 antikoerper, de2f1 antikoerper, def21 antikoerper, drosE2F1 antikoerper, e2f antikoerper, e2f1 antikoerper, l(3)07172 antikoerper, l(3)j3B1 antikoerper, l(3)j3C2 antikoerper, l(3)rM729 antikoerper, RBAP1 antikoerper, RBBP3 antikoerper, RBP3 antikoerper, mKIAA4009 antikoerper, xE2F antikoerper, ATE2FB antikoerper, E2F TRANSCRIPTION FACTOR-1 E2F1 antikoerper, E2F transcription factor 1 antikoerper, E2FB antikoerper, E2FB TRANSCRIPTION FACTOR antikoerper, E2F transcription factor 1 antikoerper, E2F transcription factor 1 L homeolog antikoerper, E2f1 antikoerper, E2F1 antikoerper, e2f1.L antikoerper
- Hintergrund
- Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
- UniProt
- Q01094
- Pathways
- p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
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