Tyrosinase-Related Protein 1 Antikörper (TRP1)

Produktnummer ABIN5708054

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Tyrosinase-Related Protein 1 in IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (TRP1) (ABIN5708054)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: TYRP1-1564R

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Bindungsspezifität: TRP1

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: Human recombinant protein used as the immunogen for this recombinant TYRP1 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The optimal dilution of the recombinant TYRP1 antibody for each application should be determined by the researcher.\. Immunohistochemistry (FFPE) : 5-10 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant TYRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: Tyrosinase-Related Protein-1

Hintergrund: Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.