LDHB Antikörper

Produktnummer ABIN5698058

Der Kaninchen Polyklonal anti-LDHB Antikörper wird verwendet zum Nachweis von LDHB in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC, IP, IF, ELISA und FACS.

Kurzübersicht für LDHB Antikörper (ABIN5698058)

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Produktdetails anti-LDHB Antikörper

Verwendungszweck: LDHB antibody

Immunogen: lactate dehydrogenase B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab04738(LDHB antibody) at dilution of 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu LDHB

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Andere Bezeichnung: LDHB

Hintergrund:

Synonyms: L-lactate dehydrogenase B chain (LDH-B)|LDH heart subunit (LDH-H)|Renal carcinoma antigen NY-REN-46|LDHB

Background: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Molekulargewicht: 35 kDa

Gen-ID: 3945

UniProt: P07195

Pathways: Warburg Effekt