MCL-1 Antikörper

Produktnummer ABIN5697987

Dieser Anti-MCL-1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MCL-1 in WB, ELISA, IHC und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MCL-1 Antikörper (ABIN5697987)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCL-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-MCL-1 Antikörper

Verwendungszweck: MCL1 antibody

Immunogen: myeloid cell leukemia sequence 1 (BCL2-related)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Raji cells were subjected to SDS PAGE followed by western blot with FNab05052(MCL1 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Andere Bezeichnung: MCL1

Hintergrund:

Synonyms: Induced myeloid leukemia cell differentiation protein Mcl-1|Bcl-2-like protein 3 (Bcl2-L-3)|Bcl-2-related protein EAT/mcl1|mcl1/EAT|MCL1|BCL2L3

Background: This gene encodes an anti- apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Molekulargewicht: 40 kDa

Gen-ID: 4170

UniProt: Q07820

Pathways: MAPK Signalweg