Der Kaninchen Polyklonal anti-CDC25A Antikörper (ABIN5689805) detektiert spezifisch CDC25A in WB und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
This antibody detects endogenous level of cdc25A only when phosphorylated at serine 76.
Aufreinigung
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Immunogen
cdc25A (Phospho-Ser76) antibody was raised against a peptide sequence around phosphorylation site of serine 76 (M-G-S (p) -S-E) derived from Human cdc25A.
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store antibody at -20°C for up to one year.
Target
CDC25A
(Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
Andere Bezeichnung
cdc25A
Hintergrund
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.