E2F1 Antikörper (AA 430-434)
Kurzübersicht für E2F1 Antikörper (AA 430-434) (ABIN5689264)
Target
Alle E2F1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 430-434
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Spezifität
- This antibody detects endogenous levels of total E2F-1 protein.
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Aufreinigung
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- E2F-1 antibody was raised against a peptide sequence around aa.430~434 (G-D-L-T-P) derived from Human E2F-1.
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anti-E2F Transcription Factor 1 (E2F1) (AA 69-223) antibody
E2F1 Reaktivität: Human, Maus WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 8G9 unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Monoclonal 1D12 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 1 (E2F1) (AA 348-437) antibodyE2F1 Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2E10 unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 133-362) antibodyE2F1 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 101-180) antibodyE2F1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (p), IF (cc), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibodyE2F1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB7913 unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 Reaktivität: Human WB, IF, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibodyE2F1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibodyE2F1 Reaktivität: Human WB, ELISA, FACS, IF (p), IF (cc), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pThr433) antibodyE2F1 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Western Blot: 1:500~1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store antibody at -20°C for up to one year.
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- E2F1 (E2F Transcription Factor 1 (E2F1))
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Andere Bezeichnung
- E2F 1
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Hintergrund
- Transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis.
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Molekulargewicht
- 70 kDa
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Gen-ID
- 1869
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NCBI Accession
- NP_005216
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UniProt
- Q01094
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Pathways
- p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
Target
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