PLK1 Antikörper (pThr210)

Produktnummer ABIN5688913

Produktdetails anti-PLK1 Antikörper

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Bindungsspezifität: pThr210

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity Purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr210 of PLK1.

Anwendungsinformationen

Applikationshinweise: The antibody has been directly tested for reactivity in Western blots in rat and human tissues. It is anticipated that the antibody will react with bovine, canine, mouse, non-human primate, Xenopus and Zebrafish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: PLK1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Details zu PLK1

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Andere Bezeichnung: PLK1 (PLK1 Produkte)

Synonyme: PLK antikoerper, STPK13 antikoerper, plk antikoerper, PLK-1 antikoerper, Plx1 antikoerper, stpk13 antikoerper, Plk antikoerper, cb525 antikoerper, cb636 antikoerper, ik:tdsubc_2d1 antikoerper, wu:fb37g11 antikoerper, wu:fb76g03 antikoerper, xx:tdsubc_2d1 antikoerper, polo like kinase 1 antikoerper, polo like kinase 1 S homeolog antikoerper, polo-like kinase 1 antikoerper, polo-like kinase 1 (Drosophila) antikoerper, Serine/threonine-protein kinase plk-1 antikoerper, PLK1 antikoerper, plk1.S antikoerper, plk1 antikoerper, Plk1 antikoerper, plk-1 antikoerper

Hintergrund: Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles (van Vugt et al., 2004). Deregulated expression of PLK's is detected in many types of cancer and associated with oncogenesis (Takei et al., 2005). It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210 (van de Weerdt et al., 2005).

Molekulargewicht: 66 kDa

Gen-ID: 5347

UniProt: P53350

Pathways: Zellzyklus, M Phase