LBP Antikörper
Kurzübersicht für LBP Antikörper (ABIN5663309)
Target
Alle LBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Human LBP (Lipopolysaccaride binding protein). The antibody don't block LPS binding to membrane bound CD14.
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Kreuzreaktivität
- Rind (Kuh), Hund, Pferd, Kaninchen
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Kreuzreaktivität (Details)
- pork, rabbit, dog, horse, bovine LBP
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Aufreinigung
- Protein G affinity column
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Immunogen
- native human LBP
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute with bidistilled water
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.13
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Konservierungsmittel
- Without preservative
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Lagerung
- -20 °C,-80 °C
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- LBP (Lipopolysaccharide Binding Protein (LBP))
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Andere Bezeichnung
- LBP
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Hintergrund
- Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
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Molekulargewicht
- ~58kDa
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Gen-ID
- 3929
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NCBI Accession
- NP_004130
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UniProt
- P18428
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
Target
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