IGFBP3 Antikörper

Produktnummer ABIN5647579

Der Kaninchen Polyklonal anti-IGFBP3 Antikörper wird verwendet zum Nachweis von IGFBP3 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA (Capture).

Kurzübersicht für IGFBP3 Antikörper (ABIN5647579)

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGFBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA (Capture)

Produktdetails anti-IGFBP3 Antikörper

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids A29-K267 was used as the immunogen for the IGFBP3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IGFBP3 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free formulation available)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IGFBP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IGFBP3

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Andere Bezeichnung: IGFBP3

Hintergrund: IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P17936

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Growth Factor Binding