IGFBP3 Antikörper (AA 100-200)

Produktnummer ABIN7267908

Der Kaninchen Polyklonal anti-IGFBP3 Antikörper (ABIN7267908) detektiert spezifisch IGFBP3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IGFBP3 Antikörper (AA 100-200) (ABIN7267908)

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGFBP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IGFBP3 Antikörper

Bindungsspezifität: AA 100-200

Verwendungszweck: IGFBP3 Rabbit pAb

Sequenz: EARPLQALLD GRGLCVNASA VSRLRAYLLP APPAPGNASE SEEDRSAGSV ESPSVSSTHR VSDPKFHPLH SKIIIIKKGH AKDSQRYKVD YESQSTDTQN F

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human IGFBP3 (NP_000589.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IGFBP3

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Andere Bezeichnung: IGFBP3

Hintergrund: This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,IGFBP3,BP-53,IBP3,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Cardiovascular,Angiogenesis,IGFBP3

Molekulargewicht: 31kDa/32kDa

Gen-ID: 3486

UniProt: P17936

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Growth Factor Binding