IGFBP3 Antikörper (AA 29-267)
Kurzübersicht für IGFBP3 Antikörper (AA 29-267) (ABIN5647579)
Target
Alle IGFBP3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 29-267
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Verwendungszweck
- IGFBP3 Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A recombinant human protein corresponding to amino acids A29-K267 was used as the immunogen for the IGFBP3 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the IGFBP3 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the IGFBP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
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Andere Bezeichnung
- IGFBP3
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Hintergrund
- IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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UniProt
- P17936
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Pathways
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Growth Factor Binding
Target
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