SQSTM1 Antikörper (AA 383-409)
Kurzübersicht für SQSTM1 Antikörper (AA 383-409) (ABIN3032535)
Target
Alle SQSTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 383-409
-
Kreuzreaktivität (Details)
- Expected species reactivity: Mouse, Rat
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- A portion of amino acids 383-409 from the human protein was used as the immunogen for this SQSTM1 antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- Titration of the SQSTM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the SQSTM1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- SQSTM1 (Sequestosome 1 (SQSTM1))
-
Andere Bezeichnung
- SQSTM1
-
Hintergrund
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
-
UniProt
- Q13501
-
Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Target
-