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PCNA Antikörper
PCNA
Reaktivität: Human, Maus, Ratte, Huhn, Drosophila melanogaster, Non-Human Primate
WB, FACS, IHC (p), IP, ICC, IHC (fro)
Wirt: Maus
Monoclonal
PC10
unconjugated
Produktnummer ABIN5633264
Produktdetails anti-PCNA Antikörper
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Target
Alle PCNA Antikörper anzeigen
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Reaktivität
Alle Reaktivitäten für PCNA Antikörper
Human, Maus, Ratte, Huhn, Drosophila melanogaster, Non-Human Primate
Wirt
Alle Wirte für PCNA Antikörper
Maus
Klonalität
Alle Klonalitäten für PCNA Antikörper
Monoklonal
Konjugat
Alle Konjugate für PCNA Antikörper
Dieser PCNA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PCNA Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
Spezifität
The mouse monoclonal antibody PC10 (also known as 3F81) recognizes PCNA, a 36 kDa conserved nuclear protein serving as a cofactor for DNA synthesis.
Kreuzreaktivität (Details)
Human, Non-Human Primates, Mouse, Rat, Chicken, Drosophila
Aufreinigung
Purified by protein-A affinity chromatography.
Reinheit
> 95 % (by SDS-PAGE)
Immunogen
recombinant rat PCNA
Klon
PC10
Isotyp
IgG2a kappa
Top Product
Discover our top product PCNA Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store at 2-8°C. Do not freeze.
Details zu PCNA
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Target
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Andere Bezeichnung
PCNA (PCNA Produkte )
Hintergrund
Proliferating cell nuclear antigen,PCNA (proliferating cell nuclear antigen) is the DNA polymerase delta auxiliary protein acting in homotrimeric form to increase the processivity of leading strand synthesis during DNA replication. PCNA is expressed in the nucleus of all proliferating cells. In response to DNA damage, it is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. PCNA is a useful marker of DNA synthesis, as its form not involved in DNA synthesis degradates in histological preparations in the presence of organic solvents.,ATLD2
Gen-ID
5111
UniProt
P12004
Pathways
Telomere Maintenance , DNA Reparatur , Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Autophagie
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