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PCNA Antikörper

PCNA Reaktivität: Human, Maus, Ratte, Huhn, Drosophila melanogaster, Non-Human Primate WB, FACS, IHC (p), IP, ICC, IHC (fro) Wirt: Maus Monoclonal PC10 unconjugated
Produktnummer ABIN5633264
  • Target Alle PCNA Antikörper anzeigen
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Reaktivität
    • 216
    • 152
    • 151
    • 53
    • 28
    • 27
    • 21
    • 19
    • 19
    • 18
    • 16
    • 15
    • 11
    • 10
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn, Drosophila melanogaster, Non-Human Primate
    Wirt
    • 135
    • 94
    • 3
    Maus
    Klonalität
    • 135
    • 96
    • 1
    Monoklonal
    Konjugat
    • 110
    • 17
    • 12
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCNA Antikörper ist unkonjugiert
    Applikation
    • 189
    • 68
    • 62
    • 61
    • 53
    • 48
    • 45
    • 40
    • 30
    • 14
    • 14
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    The mouse monoclonal antibody PC10 (also known as 3F81) recognizes PCNA, a 36 kDa conserved nuclear protein serving as a cofactor for DNA synthesis.
    Kreuzreaktivität (Details)
    Human, Non-Human Primates, Mouse, Rat, Chicken, Drosophila
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    recombinant rat PCNA
    Klon
    PC10
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product PCNA Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Andere Bezeichnung
    PCNA (PCNA Produkte)
    Hintergrund
    Proliferating cell nuclear antigen,PCNA (proliferating cell nuclear antigen) is the DNA polymerase delta auxiliary protein acting in homotrimeric form to increase the processivity of leading strand synthesis during DNA replication. PCNA is expressed in the nucleus of all proliferating cells. In response to DNA damage, it is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. PCNA is a useful marker of DNA synthesis, as its form not involved in DNA synthesis degradates in histological preparations in the presence of organic solvents.,ATLD2
    Gen-ID
    5111
    UniProt
    P12004
    Pathways
    Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie
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