c-MET Antikörper (C-Term)
Kurzübersicht für c-MET Antikörper (C-Term) (ABIN5611438)
Target
Alle c-MET (MET) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody reacts to Hepatocyte Growth Factor Receptor (MET).
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Aufreinigung
- Immunoaffinity Chromatography
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Immunogen
- MET antibody was raised against a synthetic peptide from C-terminus of human c-Met protein Genename: MET
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0,2 mg/mL
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Buffer
- 10 mM PBS/1 % BSA buffer pH 7.4 with 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- c-MET (MET) (Met Proto-Oncogene (MET))
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Andere Bezeichnung
- HGF Receptor
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Hintergrund
- Met, an HGF Receptor/Met type protein kinase, is a cell-surface proto-oncogene that mediates the biological activities of hepatocyte growth factor. The protein is a disulfide-linked heterodimer comprised of two subunits: a 50 kD extracellular alpha subunit and a membrane-spanning 145 kD beta subunit that binds ligand. Met is an important regulator of cell proliferation and differentiation, organ regeneration, embryogenesis, and tumorogenesis. Constitutive activation mutations of the met gene lead to many cancers, particularly renal papillary carcinoma.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met
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Gen-ID
- 4233
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NCBI Accession
- NP_000236
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UniProt
- P08581
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Pathways
- RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
Target
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