BAX Antikörper (AA 13-160)
Kurzübersicht für BAX Antikörper (AA 13-160) (ABIN5611252)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 13-160
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Verwendungszweck
- BAX Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human BAX (AA: 13-160) expressed in E. Coli.
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Isotyp
- IgG2a
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Huhn, Zebrafisch (Danio rerio) WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB0952 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reaktivität: Human, Maus, Ratte, Affe, Schwein, Rind (Kuh), Kaninchen, Hund, Huhn, Schaf, Pferd, Meerschweinchen, Ziege, Hamster, Avian, Cat, Esel WB, IF Wirt: Ziege Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 2G6B2 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX Reaktivität: Human WB, ELISA, IF, IHC (p), PLA Wirt: Maus Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reaktivität: Human, Schwein, Rind (Kuh), Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- BAX
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Hintergrund
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The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
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Molekulargewicht
- 21.2 kDa
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Gen-ID
- 581
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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