PRKAB2 Antikörper (AA 1-120)
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- Target Alle PRKAB2 Antikörper anzeigen
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
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Bindungsspezifität
- AA 1-120
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PRKAB2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- PRKAB2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PRKAB2 (AA: 1-120) expressed in E. Coli.
- Klon
- 8F5B2
- Isotyp
- IgG1
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anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-120) antibody
PRKAB2 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 7A8C3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2G9 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 56-89), (N-Term) antibodyPRKAB2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 3-33), (N-Term) antibodyPRKAB2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB3183 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-110) antibodyPRKAB2 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 17-260) antibodyPRKAB2 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 17-260) antibodyPRKAB2 Reaktivität: Human WB, IHC, IF/ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) antibodyPRKAB2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
- Andere Bezeichnung
- PRKAB2 (PRKAB2 Produkte)
- Hintergrund
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
- Molekulargewicht
- 30.3kDa
- Gen-ID
- 5565
- HGNC
- 5565
- UniProt
- O43741
- Pathways
- AMPK Signaling, Warburg Effekt
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