CDK2 Antikörper

Produktnummer ABIN5557541

Dieses Anti-CDK2-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von CDK2 in WB und IHC (p). Geeignet für Maus und Ratte.

Kurzübersicht für CDK2 Antikörper (ABIN5557541)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CDK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2E3

Produktdetails anti-CDK2 Antikörper

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant human Cdk2 protein, around C-terminal 100aa.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-5000
IHC-P 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C

Haltbarkeit: 12 months

Details zu CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Andere Bezeichnung: Cdk2

Hintergrund:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

Synonyms: CDKN2, p33(CDK2), Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase, CDK2

Gen-ID: 1017

UniProt: P24941

Pathways: PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA