Rekombinanter PIK3R1 Antikörper
Kurzübersicht für Rekombinanter PIK3R1 Antikörper (ABIN5557516)
Target
Alle PIK3R1 (PI3K p85a) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- PIK3R1 Recombinant Antibody
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant human PI 3 Kinase p85 alpha protein, around 600-700aa.
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
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Andere Bezeichnung
- PI 3 Kinase p85 alpha
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Hintergrund
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Synonyms: p85, AGM7, GRB1, IMD36, p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PIK3R1
Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
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Gen-ID
- 5295
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UniProt
- P27986
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Pathways
- T-Zell Rezeptor Signalweg, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effekt
Target
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