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Caspase 3 Antikörper (AA 29-175)

CASP3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3D4D10 unconjugated
Produktnummer ABIN5542609
  • Target Alle Caspase 3 (CASP3) Antikörper anzeigen
    Caspase 3 (CASP3)
    Bindungsspezifität
    • 20
    • 16
    • 16
    • 14
    • 12
    • 12
    • 10
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-175
    Reaktivität
    • 197
    • 117
    • 72
    • 15
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 208
    • 24
    • 3
    • 2
    • 2
    Maus
    Klonalität
    • 203
    • 35
    Monoklonal
    Konjugat
    • 143
    • 19
    • 17
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Caspase 3 Antikörper ist unkonjugiert
    Applikation
    • 173
    • 96
    • 92
    • 59
    • 41
    • 33
    • 29
    • 28
    • 27
    • 26
    • 25
    • 11
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Verwendungszweck
    CASP3 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CASP3 (AA: 29-175) expressed in E. Coli.
    Klon
    3D4D10
    Isotyp
    IgG1
    Top Product
    Discover our top product CASP3 Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    Caspase 3 (CASP3)
    Andere Bezeichnung
    CASP3 (CASP3 Produkte)
    Hintergrund

    Description: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

    Aliases: CPP32, SCA-1, CPP32B

    Molekulargewicht
    31.6kDa
    Gen-ID
    836
    HGNC
    836
    UniProt
    P42574
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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