Caspase 3 Antikörper (AA 29-175)

Produktnummer ABIN5542609

Dieses Anti-Caspase 3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Caspase 3 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Caspase 3 Antikörper (AA 29-175) (ABIN5542609)

Target: Caspase 3 (CASP3)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Caspase 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 3D4D10

Produktdetails anti-Caspase 3 Antikörper

Bindungsspezifität: AA 29-175

Verwendungszweck: CASP3 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CASP3 (AA: 29-175) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Caspase 3

Target: Caspase 3 (CASP3)

Andere Bezeichnung: CASP3

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Molekulargewicht: 31.6 kDa

Gen-ID: 836

UniProt: P42574

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation