PARP1 Antikörper (AA 373-540)
Kurzübersicht für PARP1 Antikörper (AA 373-540) (ABIN5541684)
Target
Alle PARP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 373-540
-
Spezifität
- The antibody recognizes Human PARP. Other species not tested.
-
Aufreinigung
- Affinity Chromatography on Protein A/G
-
Immunogen
- E.coli -derived recombinant human PARP- Thr 373-Glu 540
-
Isotyp
- IgG1
-
-
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibody
PARP1 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyKO Validated PARP1 Reaktivität: Human WB, IP, IF, ICC, IHC (p), ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibodyPARP1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibodyPARP1 Reaktivität: Human, Maus, Ratte, Huhn WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibodyPARP1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3G4 unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibodyPARP1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyPARP1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Monoclonal 8C7 unconjugated Recombinant Antibody
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibodyPARP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (N-Term) antibodyPARP1 Reaktivität: Human WB, IHC, 2D-PAGE Wirt: Kaninchen Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibodyPARP1 Reaktivität: Human WB, 2D-PAGE Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- Western Blot: 1 μg/mL. Positive Control : HeLa cell lysate. Immunohistochemistry on Paraffin Sections: 8-25 μg/mL. Positive Control: Human breast tissue.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Sterile PBS
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
-
Haltbarkeit
- 12 months
-
-
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
-
Andere Bezeichnung
- parp1
-
Hintergrund
- PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved by many ICE-like Caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP amino-terminal DNA binding domain (24 kDa) from the carboxy-terminal catalytic domain (89 kDa). PARP helps cells to maintain their viability cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis.
-
UniProt
- P09874
-
Pathways
- Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Target
-
