14-3-3 sigma/SFN Antikörper (C-Term)

Produktnummer ABIN5541548

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch 14-3-3 sigma/SFN in WB, IF, FACS, ICC und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für 14-3-3 sigma/SFN Antikörper (C-Term) (ABIN5541548)

Target: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 sigma/SFN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-14-3-3 sigma/SFN Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody recognizes Human SFN (C-term). Other species not tested.

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 222-248 amino acids from the C-terminal region of Human SFN.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blotting: 1/1000. Immunohistochemistry on Paraffin Sections: 1/10-1/50. Flow Cytometry: Immunofluorescence:

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS Preservatives: 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu 14-3-3 sigma/SFN

Target: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Andere Bezeichnung: 14-3-3 protein sigma,sfn

Hintergrund: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axolly transported to the nerve termils. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of sigl transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in sigling pathways mediated by serine/threonine protein kises. Evidence indicates 14-3-3 is required for Raf 1 kise activity and phosphorylation among many other functions.

UniProt: P31947

Pathways: p53 Signalweg, Myometrial Relaxation and Contraction