GDNF Antikörper

Produktnummer ABIN5540934

Der Maus Monoklonal Anti-GDNF-Antikörper wurde für WB, ICC, IHC (p), IF und EIA validiert. Er ist geeignet, GDNF in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für GDNF Antikörper (ABIN5540934)

Target: GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GDNF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Klon: 3C1

Produktdetails anti-GDNF Antikörper

Spezifität: Recognizes Human GDNF. Other species not tested.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Recombinant human GDNF protein produced using E. coli expression system.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 50-100 ng/mL. Western Blot: 2-5 μg/mL. Immunofluorescence: 2-10 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.4 Preservatives: 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-GDNF Antikörper (ABIN5540934)

Lin, Hsieh, Chen, Wu, Tsai, Huang, Hua, Wei, Yeh, Liu: "Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 235, pp. 72-81, (2016) (PubMed).

Details zu GDNF

Target: GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Andere Bezeichnung: gdnf

Hintergrund: GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex.

UniProt: P39905

Pathways: RTK Signalweg, Synaptic Membrane, Tube Formation, Autophagie, Smooth Muscle Cell Migration