IL9 Receptor Antikörper

Produktnummer ABIN5540440

Dieses Anti-IL9 Receptor-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL9 Receptor in FACS, Func und EIA. Geeignet für Human.

Kurzübersicht für IL9 Receptor Antikörper (ABIN5540440)

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL9 Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)

Klon: AH9R7

Produktdetails anti-IL9 Receptor Antikörper

Spezifität: This antibody recognizes CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.

Aufreinigung: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)

Immunogen: Human CD129-transfected cell line

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Use bright fluorochromes or signal multiplying detection. ELISA. Functional application: blocking.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu IL9 Receptor

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Andere Bezeichnung: cd129,il9r

Hintergrund: CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.

UniProt: Q01113

Pathways: JAK-STAT Signalweg, Growth Factor Binding