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IL9 Receptor Antikörper (PE)

IL9R Reaktivität: Human FACS Wirt: Maus Monoclonal AH9R7 PE
Produktnummer ABIN2749105
  • Target Alle IL9 Receptor (IL9R) Antikörper anzeigen
    IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
    Reaktivität
    • 43
    • 18
    • 2
    Human
    Wirt
    • 33
    • 11
    • 2
    Maus
    Klonalität
    • 32
    • 13
    • 1
    Monoklonal
    Konjugat
    • 27
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL9 Receptor Antikörper ist konjugiert mit PE
    Applikation
    • 28
    • 25
    • 23
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Human CD129-transfected cell line
    Klon
    AH9R7
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product IL9R Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Pilette, Ouadrhiri, Van Snick, Renauld, Staquet, Vaerman, Sibille: "Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).

    Pilette, Ouadrhiri, Van Snick, Renauld, Staquet, Vaerman, Sibille: "IL-9 inhibits oxidative burst and TNF-alpha release in lipopolysaccharide-stimulated human monocytes through TGF-beta." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 4103-11, (2002) (PubMed).

    De Smedt, Verhasselt, Kerre, Vanhecke, Naessens, Leclercq, Renauld, Van Snick, Plum: "Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1761-7, (2000) (PubMed).

  • Target
    IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
    Andere Bezeichnung
    CD129 / IL-9R alpha (IL9R Produkte)
    Synonyme
    CD129 antikoerper, IL-9R antikoerper, interleukin 9 receptor antikoerper, IL9R antikoerper, Il9r antikoerper
    Hintergrund
    Interleukin 9 receptor,CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.,IL9R
    Gen-ID
    3581
    UniProt
    Q01113
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding
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