Cyclin H Antikörper (AA 1-323)

Produktnummer ABIN5540277

Der Maus Monoklonal Anti-Cyclin H-Antikörper wurde für WB und EIA validiert. Er ist geeignet, Cyclin H in Proben von Human zu detektieren.

Kurzübersicht für Cyclin H Antikörper (AA 1-323) (ABIN5540277)

Target: Cyclin H (CCNH)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cyclin H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: AT3G6

Produktdetails anti-Cyclin H Antikörper

Bindungsspezifität: AA 1-323

Aufreinigung: Protein-A affinity chromatography

Immunogen: Recombinant human Cyclin H (1-323aa) purified from E.coli.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution for Western blot analysis is 1:1000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Cyclin H

Target: Cyclin H (CCNH)

Andere Bezeichnung: cyclin h

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kises. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordition of each mitotic event. This cyclin forms a complex with CDK7 kise and ring finger protein MAT1. The kise complex is able to phosphorylate CDK2 and CDC2 kises, thus functions as a CDK-activating kise (CAK). This cyclin and its kise partner are components of TFIIH, as well as R polymerase II protein complexes. They participate in two different transcriptiol regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery.

UniProt: P51946

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase