FZD7 Antikörper (AA 202-229)

Produktnummer ABIN5536129

Dieses Anti-FZD7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FZD7 in WB. Geeignet für Human.

Kurzübersicht für FZD7 Antikörper (AA 202-229) (ABIN5536129)

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FZD7 Antikörper

Bindungsspezifität: AA 202-229

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.488 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu FZD7

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Andere Bezeichnung: FZD7

Hintergrund: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Molekulargewicht: 64 kDa

Gen-ID: 8324

UniProt: O75084

Pathways: WNT Signalweg, Stem Cell Maintenance