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Leptin Antikörper (AA 22-167)

Zitiert in 1 Publikation. Dieser Anti-Leptin-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von Leptin in WB und ELISA. Geeignet für Ratte.
Produktnummer ABIN5518931
500,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 11 Werktagen

Kurzübersicht für Leptin Antikörper (AA 22-167) (ABIN5518931)

Target

Alle Leptin (LEP) Antikörper anzeigen
Leptin (LEP)

Reaktivität

  • 131
  • 76
  • 70
  • 12
  • 7
  • 7
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Ratte

Wirt

  • 175
  • 35
  • 7
  • 5
  • 2
  • 2
  • 1
Kaninchen

Klonalität

  • 188
  • 38
Polyklonal

Konjugat

  • 119
  • 25
  • 13
  • 9
  • 7
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Leptin Antikörper ist unkonjugiert

Applikation

  • 137
  • 81
  • 73
  • 41
  • 39
  • 39
  • 35
  • 32
  • 28
  • 18
  • 14
  • 11
  • 10
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 27
    • 16
    • 15
    • 15
    • 9
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-167

    Verwendungszweck

    Anti-Leptin Antibody

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Leptin Antibody (ABIN5518931). Tested in ELISA, WB applications. This antibody reacts with Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived rat Leptin recombinant protein (Position: V22-C167). Rat Leptin shares 83.6% and 95.9% amino acid (aa) sequence identity with human and mouse Leptin, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA, 0.1-0.5 μg/mL, Western blot, 0.1-0.5 μg/mL, Rat,

    Kommentare

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Li, Zhao, Qi, Wang, Zhang, Li, Qin: "lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).

  • Target

    Leptin (LEP)

    Andere Bezeichnung

    Lep

    Hintergrund

    Synonyms: Leptin,Obesity factor,Lep,Ob,

    Tissue Specificity: Expressed in the parathyroid.

    Background: Leptin have been found to be obese and diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding Leptin have been isolated from human, simian, mouse, and rat cells. The expression of Leptin mRNA has been shown to be restricted to adipose tissue. Although regulation of fat stores is deemed to be the primary function of leptin, it also plays a role in other physiological processes, as evidenced by its multiple sites of synthesis other than fat cells, and the multiple cell types beside hypothalamic cells that have leptin receptors. Many of these additional functions are yet to be defined.

    Molekulargewicht

    16 kDa

    Gen-ID

    25608

    UniProt

    P50596

    Pathways

    JAK-STAT Signalweg, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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