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Phospholipase C gamma 1 Antikörper (C-Term)
PLCG1
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5517384
Produktdetails anti-Phospholipase C gamma 1 Antikörper
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Target
Alle Phospholipase C gamma 1 (PLCG1) Antikörper anzeigen
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Bindungsspezifität
Alle Epitope für Phospholipase C gamma 1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für Phospholipase C gamma 1 Antikörper
Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
Wirt
Alle Wirte für Phospholipase C gamma 1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Phospholipase C gamma 1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für Phospholipase C gamma 1 Antikörper
Dieser Phospholipase C gamma 1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Phospholipase C gamma 1 Antikörper
Western Blotting (WB)
Sequenz
RGIVCPFVEI EVAGAEYDST KQKTEFVVDN GLNPVWPAKP FHFQISNPEF
Homologie
Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale
This is a rabbit polyclonal antibody against PLCG1. It was validated on Western Blot.
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PLCG1
Top Product
Discover our top product PLCG1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu Phospholipase C gamma 1
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Target
Phospholipase C gamma 1 (PLCG1)
(phospholipase C, gamma 1 (PLCG1))
Andere Bezeichnung
PLCG1 (PLCG1 Produkte )
Synonyme
NCKAP3 antikoerper, PLC-II antikoerper, PLC1 antikoerper, PLC148 antikoerper, PLCgamma1 antikoerper, plc1 antikoerper, nckap3 antikoerper, plc-ii antikoerper, plc148 antikoerper, plcgamma1 antikoerper, PPLCA antikoerper, AI894140 antikoerper, Cded antikoerper, Plc-1 antikoerper, Plc-gamma1 antikoerper, Plcg-1 antikoerper, fj46f04 antikoerper, wu:fj46f04 antikoerper, wu:fj57a05 antikoerper, phospholipase C gamma 1 antikoerper, phospholipase C gamma 1 L homeolog antikoerper, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 antikoerper, phospholipase C, gamma 1 antikoerper, PLCG1 antikoerper, plcg1.L antikoerper, LOC100633163 antikoerper, Plcg1 antikoerper, plcg1 antikoerper
Hintergrund
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. Alias Symbols: PLC1 Protein Interaction Partner: EGFR, UBC, SARNP, WDR61, RIC8A, AASDHPPT, UBR7, EHD4, DPP7, GTF3C4, LIMD1, RPL38, PYGB, ZAP70, KHDRBS1, RASA1, JAK2, JAK1, LCP2, ERBB3, ERBB2, CBL, LAT, VAV1, PDGFRB, INSR, IRS2, NTMT1, SPRY1, NPM1, NCAM1, ALK, PML, IBTK, EEF1A1, BLNK, BAG3, EPOR, CAMK2A, Protein Size: 1290
Gen-ID
5335
UniProt
P19174
Pathways
RTK Signalweg , WNT Signalweg , T-Zell Rezeptor Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Thyroid Hormone Synthesis , Inositol Metabolic Process , Myometrial Relaxation and Contraction , Regulation of Muscle Cell Differentiation , Regulation of G-Protein Coupled Receptor Protein Signaling , Skeletal Muscle Fiber Development , G-protein mediated Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Interaction of EGFR with phospholipase C-gamma , VEGFR1 Specific Signals , VEGF Signaling
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