TRF1 Antikörper (C-Term)

Produktnummer ABIN5516265

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch TRF1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen.

Kurzübersicht für TRF1 Antikörper (C-Term) (ABIN5516265)

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRF1 Antikörper

Bindungsspezifität: C-Term

Sequenz: NLRSGVRKYG EGNWSKILLH YKFNNRTSVM LKDRWRTMKK LKLISSDSED

Homologie: Cow: 91%, Dog: 91%, Horse: 91%, Human: 100%, Mouse: 90%, Pig: 91%, Rabbit: 82%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against TERF1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TERF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Andere Bezeichnung: TERF1

Hintergrund: This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Alias Symbols: TERF1, PIN2, TRBF1, TRF, TRF1,

Protein Interaction Partner: EP300, SKP1, UBC, ANXA8L1, FBXO4, U2AF1, U2AF2, KDM1A, TINF2, BTRC, TNKS, TCIRG1, SMAD9, BLM, ATM, TNKS2, PINX1, RLIM, DDX19B, PACSIN2, OGFR, TOMM34, WDR4, ARPP21, TRIM16, HEXIM1, PAICS, DNPH1, HMGN4, TUBB4B, TUBB3, AKR1A1, RTN3, PAK4, STUB1, DDX39A, DPP3

Protein Size: 439

Gen-ID: 7013

NCBI Accession: NP_059523

UniProt: P54274

Pathways: Zellzyklus, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity