TRF1 Antikörper (AA 240-419)
Kurzübersicht für TRF1 Antikörper (AA 240-419) (ABIN1683138)
Target
Alle TRF1 (TERF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 240-419
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Sequenz
- IKSYVNYVLS EKSSTFLMKA AAKVVESKRT RTITSQDKPS GNDVEMETEA NLDTRKRSHK NLFLSKLQHG TQQQDLNKKE RRVGTPQSTK KKKESRRATE SRIPVSKSQP VTPEKHRARK RQAWLWEEDK NLRSGVRKYG EGNWSKILLH YKFNNRTSVM LKDRWRTMKK LKLISSDSED
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 240-419 of human TERF1 (NP_003209.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
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Andere Bezeichnung
- TERF1
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Hintergrund
- This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.,TERF1,PIN2,TRBF1,TRF,TRF1,hTRF1-AS,t-TRF1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,TERF1
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Molekulargewicht
- 48 kDa/50 kDa
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Gen-ID
- 7013
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UniProt
- P54274
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Pathways
- Zellzyklus, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
Target
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