IL1A Antikörper (N-Term)

Produktnummer ABIN5515428

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IL1A in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Ziege und Kaninchen.

Kurzübersicht für IL1A Antikörper (N-Term) (ABIN5515428)

Target: IL1A (Interleukin 1 alpha (IL1A))

Reaktivität: Human, Ratte, Maus, Ziege, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL1A Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: IL1A Antibody - N-terminal region

Sequenz: VPDMFEDLKN CYSENEEDSS SIDHLSLNQK SFYHVSYGPL HEGCMDQSVS

Homologie: Goat: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human IL1A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54321-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Andere Bezeichnung: IL1A

Hintergrund:

Background Information: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Gene Name: interleukin 1, alpha

Alternative Symbols: IL1, IL-1A, IL1F1, IL1-ALPHA, IL-1 alpha

Protein Name: Interleukin-1 alpha

Molekulargewicht: 29kDa

Gen-ID: 3552

NCBI Accession: NP_000566

UniProt: P01583

Pathways: NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints