C5AR1 Antikörper (N-Term)

Produktnummer ABIN5514594

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch C5AR1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für C5AR1 Antikörper (N-Term) (ABIN5514594)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C5AR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-C5AR1 Antikörper

Bindungsspezifität: N-Term

Sequenz: SFNYTTPDYG HYDDKDTLDL NTPVDKTSNT LRVPDILALV IFAVVFLVGV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C5AR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Andere Bezeichnung: C5AR1

Hintergrund: This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants.

Alias Symbols: BPLP, PRL1, opiorphin,

Protein Size: 350

Gen-ID: 58503

NCBI Accession: NM_001736, NP_001727

UniProt: P21730

Pathways: Komplementsystem