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Complement Factor B Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Complement Factor B in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Schaf.
Produktnummer ABIN5514558

Kurzübersicht für Complement Factor B Antikörper (N-Term) (ABIN5514558)

Target

Alle Complement Factor B (CFB) Antikörper anzeigen
Complement Factor B (CFB)

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt

  • 98
  • 20
  • 3
  • 1
Kaninchen

Klonalität

  • 98
  • 21
  • 2
Polyklonal

Konjugat

  • 53
  • 22
  • 16
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation

  • 91
  • 41
  • 40
  • 19
  • 18
  • 18
  • 13
  • 10
  • 9
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 10
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG

    Homologie

    Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against CFAB. It was validated on Western Blot.

    Aufreinigung

    Affinity purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human CFAB
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    Complement Factor B (CFB)

    Andere Bezeichnung

    CFAB

    Hintergrund

    CFAB is a factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B- lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

    Alias Symbols: CFB, BF, BFD,

    Protein Interaction Partner: FN1, LAMC3, RPA2, ALB, CFP, C3,

    Protein Size: 764

    Gen-ID

    629

    NCBI Accession

    NP_001701

    UniProt

    P00751

    Pathways

    Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process
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