UNC93B1 Antikörper (AA 300-597)

Produktnummer ABIN5027623

Der Kaninchen Polyklonal Anti-UNC93B1-Antikörper wurde für WB validiert. Er ist geeignet, UNC93B1 in Proben von Human zu detektieren.

Kurzübersicht für UNC93B1 Antikörper (AA 300-597) (ABIN5027623)

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC93B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UNC93B1 Antikörper

Bindungsspezifität: AA 300-597

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant UNC93B protein (amino acids 300-597) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 4-6 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu UNC93B1

Target: UNC93B1 (Unc-93 Homolog B1 (UNC93B1))

Andere Bezeichnung: UNC93B

Hintergrund: Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene. Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling also they helps in transportation of TLRs (basically TLR7 and TLR9) from endoplasmic reticulum to endolysosomes. Diseases associated with UNC93B1 include herpes simplex encephalitis 1, and herpes simplex encephalitis. It is expressed in plasmocytoid dendritic cells (at protein level),antigen-presenting cells(high) and at lower level in kidney.

Molekulargewicht: 70 kDa

Gen-ID: 81622

UniProt: Q9H1C4

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades